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Ppargtm1.2Gonz
Targeted Allele Detail
Nomenclature
Symbol: Ppargtm1.2Gonz
Name: peroxisome proliferator activated receptor gamma; targeted mutation 1.2, Frank J Gonzales
MGI ID: MGI:2384213
Gene: Pparg  Location: Chr6:115360951-115490399 bp, + strand  Genetic Position: Chr6, 53.41 cM, cytoband E3-F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138838
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination was used to delete exon 2. The absence of transcript expression was confirmed by RT-PCR on aorta extracts. (J:138838)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pparg Mutation:  22 strains or lines available
References
Original:  J:138838 de Lange WJ, et al., Germ Line Activation of the Tie2 and SMMHC Promoters Causes Non-Cell Specific Deletion of Floxed Alleles. Physiol Genomics. 2008 Jul 8;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory