Pparg^tm1.2Gonz
Targeted Allele Detail

Summary

• Symbol: Pparg^tm1.2Gonz
• Name: peroxisome proliferator activated receptor gamma; targeted mutation 1.2, Frank J Gonzales
• MGI ID: MGI:2384213
• Gene: Pparg Location: Chr6:115337912-115467360 bp, + strand Genetic Position: Chr6, 53.41 cM, cytoband E3-F1
• Alliance: Pparg^tm1.2Gonz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138838
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to delete exon 2. The absence of transcript expression was confirmed by RT-PCR on aorta extracts. (J:138838)

Tumor Data

List all tumor models in MMHCdb carrying Pparg^tm1.2Gonz

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pparg Mutation: 39 strains or lines available

References

• Original: J:138838 de Lange WJ, et al., Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles. Physiol Genomics. 2008 Sep 17;35(1):1-4
• All: 2 reference(s)