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Pafah1b1tm2.2Awb
Targeted Allele Detail
Nomenclature
Symbol: Pafah1b1tm2.2Awb
Name: platelet-activating factor acetylhydrolase, isoform 1b, subunit 1; targeted mutation 2.2, Anthony Wynshaw-Boris
MGI ID: MGI:2384063
Synonyms: Pafah1b1-del, Pafah1b1delex3-6
Gene: Pafah1b1  Location: Chr11:74673949-74724670 bp, - strand  Genetic Position: Chr11, 45.76 cM, cytoband B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:49531
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pafah1b1 Mutation:  147 strains or lines available
References
Original:  J:49531 Hirotsune S, et al., Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality [see comments]. Nat Genet. 1998 Aug;19(4):333-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory