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Vegfatm2.1Nagy
Targeted Allele Detail
Nomenclature
Symbol: Vegfatm2.1Nagy
Name: vascular endothelial growth factor A; targeted mutation 2.1, Andras Nagy
MGI ID: MGI:2383985
Synonyms: VEGFhypo, Vegflo
Gene: Vegfa  Location: Chr17:46016993-46032369 bp, - strand  Genetic Position: Chr17, 22.79 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75937
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Intragenic deletion
 
Mutation detailsThe mutant is a derivative of Vegf1tm2Nagy where the floxed PGK-neo cassette in exon 8 has been removed by mating to a cre deletor strain. (J:75937)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 88 assay results
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vegfa Mutation:  20 strains or lines available
References
Original:  J:75937 Damert A, et al., Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation. Development. 2002 Apr;129(8):1881-92
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory