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Tsc1tm1.1Djk
Targeted Allele Detail
Nomenclature
Symbol: Tsc1tm1.1Djk
Name: tuberous sclerosis 1; targeted mutation 1.1, David J Kwiatkowski
MGI ID: MGI:2183900
Synonyms: Tsc1-
Gene: Tsc1  Location: Chr2:28641228-28691167 bp, + strand  Genetic Position: Chr2, 19.38 cM, cytoband B-C1.1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75243
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tsc1 Mutation:  28 strains or lines available
References
Original:  J:75243 Kwiatkowski DJ, et al., A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum Mol Genet. 2002 Mar 1;11(5):525-34
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory