About   Help   FAQ
Itgb4tm1Efu
Targeted Allele Detail
Nomenclature
Symbol: Itgb4tm1Efu
Name: integrin beta 4; targeted mutation 1, Elaine Fuchs
MGI ID: MGI:2183630
Synonyms: beta4-
Gene: Itgb4  Location: Chr11:115974709-116008412 bp, + strand  Genetic Position: Chr11, 80.91 cM
Separation at the mesenchymal-epithelial junctions in skin of Itgb4tm1Efu/Itgb4tm1Efu mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77644
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itgb4 Mutation:  5 strains or lines available
References
Original:  J:77644 Dowling J, et al., Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival. J Cell Biol. 1996 Jul;134(2):559-72
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory