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Agrptm1Sqn
Targeted Allele Detail
Nomenclature
Symbol: Agrptm1Sqn
Name: agouti related neuropeptide; targeted mutation 1, Su Qian
MGI ID: MGI:2183577
Synonyms: Agrp-
Gene: Agrp  Location: Chr8:105566698-105637393 bp, - strand  Genetic Position: Chr8, 53.04 cM, cytoband D1-D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:78034
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region was replaced with a neomycin selection cassette. Transcript was undetected in homozygous mutant mice via in situ hybridization. (J:78034)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Agrp Mutation:  11 strains or lines available
References
Original:  J:78034 Qian S, et al., Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice. Mol Cell Biol. 2002 Jul;22(14):5027-35
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory