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Tgfbr2tm1Karl
Targeted Allele Detail
Nomenclature
Symbol: Tgfbr2tm1Karl
Name: transforming growth factor, beta receptor II; targeted mutation 1, Stefan Karlsson
MGI ID: MGI:2183502
Synonyms: floxed-TbetaRII, T-Beta-RII flox, Tgfbr2fl, Tgfbr2fl
Gene: Tgfbr2  Location: Chr9:116087698-116175363 bp, - strand  Genetic Position: Chr9, 68.39 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77844
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Floxed/Frt)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tgfbr2 Mutation:  5 strains or lines available
References
Original:  J:77844 Leveen P, et al., Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable. Blood. 2002 Jul 15;100(2):560-8
All:  30 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory