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Pgftm1Pec
Targeted Allele Detail
Nomenclature
Symbol: Pgftm1Pec
Name: placental growth factor; targeted mutation 1, Peter Carmeliet
MGI ID: MGI:2183459
Synonyms: P1GF-, Pgf-, PIGF-, Plgf-
Gene: Pgf  Location: Chr12:85166637-85177785 bp, - strand  Genetic Position: Chr12, 39.58 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77481
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 3 through 6 were replaced by a neomycin selection cassette. (J:77481)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pgf Mutation:  4 strains or lines available
References
Original:  J:77481 Carmeliet P, et al., Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med. 2001 May;7(5):575-83
All:  31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory