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Gucy2etm1Gar
Targeted Allele Detail
Nomenclature
Symbol: Gucy2etm1Gar
Name: guanylate cyclase 2e; targeted mutation 1, David L Garbers
MGI ID: MGI:2183212
Synonyms: GC1 KO, GC-E -, RetGC1-
Gene: Gucy2e  Location: Chr11:69218120-69237036 bp, - strand  Genetic Position: Chr11, 42.51 cM
Ultrastructure of wild type and degenerative Gucy2etm1Gar/Gucy2etm1Gar cone outer segments

Show the 2 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77627
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gucy2e Mutation:  3 strains or lines available
References
Original:  J:77627 Yang RB, et al., Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior. J Neurosci. 1999 Jul 15;19(14):5889-97
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory