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Targeted Allele Detail
Symbol: Phlda1tm1Ywc
Name: pleckstrin homology like domain, family A, member 1; targeted mutation 1, Yongwon Choi
MGI ID: MGI:2182815
Synonyms: TDAG51-
Gene: Phlda1  Location: Chr10:111506286-111508645 bp, + strand  Genetic Position: Chr10, 58.7 cM
Germline Transmission:  Earliest citation of germline transmission: J:72947
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe entire coding region (exon 1) was replaced with a neomycin resistance gene via homologous recombination. Northern blot analysis of liver RNA from homozygous mutant animals confirmed the absence of gene expression. (J:72947)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Phlda1 Mutation:  4 strains or lines available
Original:  J:72947 Rho J, et al., TDAG51 Is Not Essential for Fas/CD95 Regulation and Apoptosis In Vivo. Mol Cell Biol. 2001 Dec;21(24):8365-70
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory