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Targeted Allele Detail
Symbol: Ercc5tm1Shm
Name: excision repair cross-complementing rodent repair deficiency, complementation group 5; targeted mutation 1, Tadahiro Shiomi
MGI ID: MGI:2182793
Synonyms: Xpg-delta
Gene: Ercc5  Location: Chr1:44147744-44181260 bp, + strand  Genetic Position: Chr1, 23.55 cM, cytoband B
Germline Transmission:  Earliest citation of germline transmission: J:53756
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsExon 3 was disrupted by the insertion of a neomycin selection cassette. Neither normal nor truncated transcript was detected by Northern blot analysis of total RNA obtained from newborn homozygous mutant mice. (J:53756)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ercc5 Mutation:  37 strains or lines available
Original:  J:53756 Harada YN, et al., Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene. Mol Cell Biol. 1999 Mar;19(3):2366-72
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory