About   Help   FAQ
Zbtb16tm1Ppp
Targeted Allele Detail
Summary
Symbol: Zbtb16tm1Ppp
Name: zinc finger and BTB domain containing 16; targeted mutation 1, Pier Paolo Pandolfi
MGI ID: MGI:2182708
Synonyms: PLZF-
Gene: Zbtb16  Location: Chr9:48565597-48747522 bp, - strand  Genetic Position: Chr9, 26.47 cM
Alliance: Zbtb16tm1Ppp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:62547
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 3.5 kb genomic fragment containing the 5' coding region was replaced with a neomycin resistance cassette. Western blot analysis on extracts from homozygous mice confirmed that no detectable protein was made from this allele. (J:62547)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 24 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Zbtb16tm1Ppp
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbtb16 Mutation:  30 strains or lines available
References
Original:  J:62547 Barna M, et al., Plzf regulates limb and axial skeletal patterning. Nat Genet. 2000 Jun;25(2):166-72
All:  31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory