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Zbtb16tm1Ppp
Targeted Allele Detail
Nomenclature
Symbol: Zbtb16tm1Ppp
Name: zinc finger and BTB domain containing 16; targeted mutation 1, Pier Paolo Pandolfi
MGI ID: MGI:2182708
Synonyms: PLZF-
Gene: Zbtb16  Location: Chr9:48654297-48836222 bp, - strand  Genetic Position: Chr9, 26.47 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:62547
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 3.5 kb genomic fragment containing the 5' coding region was replaced with a neomycin resistance cassette. Western blot analysis on extracts from homozygous mice confirmed that no detectable protein was made from this allele. (J:62547)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 22 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbtb16 Mutation:  6 strains or lines available
References
Original:  J:62547 Barna M, et al., Plzf regulates limb and axial skeletal patterning. Nat Genet. 2000 Jun;25(2):166-72
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory