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Myh6tm1Jse
Targeted Allele Detail
Nomenclature
Symbol: Myh6tm1Jse
Name: myosin, heavy polypeptide 6, cardiac muscle, alpha; targeted mutation 1, Jonathan G Seidman
MGI ID: MGI:2182704
Synonyms: alphaMHC403, MHC403, R403Q
Gene: Myh6  Location: Chr14:54952246-54966927 bp, - strand  Genetic Position: Chr14, 28.01 cM
Myocyte disarray and cardiac fibrosis in Myh6tm1Jse/Myh6+ mice

Show the 1 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:32960
Parent Cell Line:  C1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (knock-in)
Mutations:    Insertion, Nucleotide substitutions
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myh6 Mutation:  80 strains or lines available
References
Original:  J:32960 Geisterfer-Lowrance AA, et al., A mouse model of familial hypertrophic cardiomyopathy. Science. 1996 May 3;272(5262):731-4
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory