About   Help   FAQ
Lbx1tm1Gld
Targeted Allele Detail
Summary
Symbol: Lbx1tm1Gld
Name: ladybird homeobox 1; targeted mutation 1, Martyn Goulding
MGI ID: MGI:2182635
Synonyms: Lbx1-, Lbx1GFP, Lbx1GFP(neo)
Gene: Lbx1  Location: Chr19:45221123-45224251 bp, - strand  Genetic Position: Chr19, 38.61 cM, cytoband D
Alliance: Lbx1tm1Gld page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:56498
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA GFP reporter gene was introduced in frame into to exon 1 at amino acid 62 followed by a loxP-flanked PGK-neo cassette via homologous recombination. The insertion causes a frameshift in the homeobox of the gene. Homozygous mutant newborn animals did not express protein product. (J:56498)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lbx1 Mutation:  13 strains or lines available
References
Original:  J:56498 Gross MK, et al., Lbx1 is required for muscle precursor migration along a lateral pathway into the limb. Development. 2000 Jan;127(2):413-24
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory