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Krt5tm1Tmm
Targeted Allele Detail
Nomenclature
Symbol: Krt5tm1Tmm
Name: keratin 5; targeted mutation 1, Thomas M Magin
MGI ID: MGI:2182612
Synonyms: K5-
Gene: Krt5  Location: Chr15:101707070-101712891 bp, - strand  Genetic Position: Chr15, 56.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:76311
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Krt5 Mutation:  11 strains or lines available
References
Original:  J:76311 Peters B, et al., Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex. Mol Biol Cell. 2001 Jun;12(6):1775-89
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory