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Cyp27b1tm1Star
Targeted Allele Detail
Nomenclature
Symbol: Cyp27b1tm1Star
Name: cytochrome P450, family 27, subfamily b, polypeptide 1; targeted mutation 1, Rene St-Arnaud
MGI ID: MGI:2182334
Synonyms: 1alpha-(OH)ase-, 1alpha-OHase-, 1alpha(OH)ase-, Cyp27b1 KO, OHase-
Gene: Cyp27b1  Location: Chr10:127048250-127053006 bp, + strand  Genetic Position: Chr10, 74.5 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71928
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cyp27b1 Mutation:  1 strain or line available
References
Original:  J:71928 Dardenne O, et al., Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets. Endocrinology. 2001 Jul;142(7):3135-41
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory