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Slc2a4tm1Abel
Targeted Allele Detail
Nomenclature
Symbol: Slc2a4tm1Abel
Name: solute carrier family 2 (facilitated glucose transporter), member 4; targeted mutation 1, E Dale Abel
MGI ID: MGI:2182083
Synonyms: G4H - (cre lox), GLUT4 lox
Gene: Slc2a4  Location: Chr11:69942539-69948188 bp, - strand  Genetic Position: Chr11, 42.93 cM, cytoband C-E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59054
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted flanking exon 10, which encodes the external and internal glucose binding sites. A neomycin selection cassette was also inserted downstream of the final coding exon. (J:59054)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc2a4 Mutation:  2 strains or lines available
References
Original:  J:59054 Abel ED, et al., Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. J Clin Invest. 1999 Dec;104(12):1703-14
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory