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Ctsdtm1Cptr
Targeted Allele Detail
Nomenclature
Symbol: Ctsdtm1Cptr
Name: cathepsin D; targeted mutation 1, Cristoph Peters
MGI ID: MGI:2182078
Synonyms: Cat D-, CD-, CDKO, CTSD-
Gene: Ctsd  Location: Chr7:142371148-142388038 bp, - strand  Genetic Position: Chr7, 87.93 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:28201
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (knock-out)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctsd Mutation:  3 strains or lines available
References
Original:  J:28201 Saftig P, et al., Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells. EMBO J. 1995 Aug 1;14(15):3599-608
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory