About   Help   FAQ
Targeted Allele Detail
Symbol: Cebpbtm1Pfj
Name: CCAAT/enhancer binding protein (C/EBP), beta; targeted mutation 1, Peter F Johnson
MGI ID: MGI:2181982
Synonyms: C/EBPbeta-, C/EBP-Beta-
Gene: Cebpb  Location: Chr2:167688915-167690418 bp, + strand  Genetic Position: Chr2, 87.58 cM
Germline Transmission:  Earliest citation of germline transmission: J:43075
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin selection cassette replaced a 1.2kb region encompassing the entire promoter and coding sequences. Western blot analysis of liver nuclear extracts showed an absence of normal protein in homozygous mutant mice. (J:43075)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 20 assay results
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cebpb Mutation:  10 strains or lines available
Original:  J:43075 Sterneck E, et al., An essential role for C/EBPbeta in female reproduction. Genes Dev. 1997 Sep 1;11(17):2153-62
All:  37 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.15
The Jackson Laboratory