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Ins2tm1Jja
Targeted Allele Detail
Nomenclature
Symbol: Ins2tm1Jja
Name: insulin II; targeted mutation 1, Jacques Jami
MGI ID: MGI:2181878
Synonyms: Ins2-, proins-2-, proinsulin 2-
Gene: Ins2  Location: Chr7:142678656-142699510 bp, - strand  Genetic Position: Chr7, 88.0 cM
Severe insulitis in Ins2tm1Jja/Ins2tm1Jja mice and lack of insulitis in Ins1tm1Jja/Ins1tm1Jja mice

Show the 3 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:40377
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 8 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Ins2 Mutation:  76 strains or lines available
References
Original:  J:40377 Duvillie B, et al., Phenotypic alterations in insulin-deficient mutant mice. Proc Natl Acad Sci U S A. 1997 May 13;94(10):5137-40
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory