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Gdf1tm1Sjl
Targeted Allele Detail
Nomenclature
Symbol: Gdf1tm1Sjl
Name: growth differentiation factor 1; targeted mutation 1, Se-Jin Lee
MGI ID: MGI:2181719
Synonyms: Gdf1-
Gene: Gdf1  Location: Chr8:70329817-70331587 bp, + strand  Genetic Position: Chr8, 34.15 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60755
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of exon 8 with a neomycin resistance cassette via homologous recombination. Homozygous mutant animals were identified by Southern blot analysis. (J:60755)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 10 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gdf1 Mutation:  5 strains or lines available
References
Original:  J:60755 Rankin CT, et al., Regulation of left-right patterning in mice by growth/differentiation factor-1. Nat Genet. 2000 Mar;24(3):262-5
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory