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Rom1tm1Mci
Targeted Allele Detail
Nomenclature
Symbol: Rom1tm1Mci
Name: rod outer segment membrane protein 1; targeted mutation 1, Roderick R McInnes
MGI ID: MGI:2181662
Synonyms: Rom1-
Gene: Rom1  Location: Chr19:8927382-8929356 bp, - strand  Genetic Position: Chr19, 6.03 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:61888
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced exon 1 and a 5' portion of exon 2. Western blot analysis of crude retinal extracts showed an absence of encoded protein in homozygous mutant mice. (J:61888)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rom1 Mutation:  5 strains or lines available
References
Original:  J:61888 Clarke G, et al., Rom-1 is required for rod photoreceptor viability and the regulation of disk morphogenesis. Nat Genet. 2000 May;25(1):67-73
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory