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Fgfr1tm3.2Cxd
Targeted Allele Detail
Summary
Symbol: Fgfr1tm3.2Cxd
Name: fibroblast growth factor receptor 1; targeted mutation 3.2, Chu-Xia Deng
MGI ID: MGI:2181474
Synonyms: Fgfr1Co, Fgfr1f
Gene: Fgfr1  Location: Chr8:26008808-26067819 bp, + strand  Genetic Position: Chr8, 14.12 cM
Alliance: Fgfr1tm3.2Cxd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75137
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThis heritable allele is a derivative of Fgfr1tm3Cxd in which the loxP flanked neomycin resistance cassette was deleted by Cre mediated recombination, leaving loxP sites flanking exons 8-14 in the final allele. (J:75137)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 10 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:  221 strains or lines available
References
Original:  J:75137 Xu X, et al., Generation of Fgfr1 conditional knockout mice. Genesis. 2002 Feb;32(2):85-6
All:  38 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory