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Targeted Allele Detail
Symbol: Cry2tm1Jhjh
Name: cryptochrome 2 (photolyase-like); targeted mutation 1, Jan H J Hoeijmakers
MGI ID: MGI:2181206
Synonyms: cry2-, mCry2-
Gene: Cry2  Location: Chr2:92403646-92434043 bp, - strand  Genetic Position: Chr2, 51.01 cM, cytoband E
Germline Transmission:  Earliest citation of germline transmission: J:54241
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin selection cassette replaced coding sequence corresponding to base pairs 397 through 810 in the cDNA sequence. RT-PCR analysis indicated a lack of transcript in homozygous mutant mice. (J:54241)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cry2 Mutation:  17 strains or lines available
Original:  J:54241 van der Horst GT, et al., Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms [see comments]. Nature. 1999 Apr 15;398(6728):627-30
All:  42 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.10
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