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Targeted Allele Detail
Symbol: Cox6a2tm1Djg
Name: cytochrome c oxidase subunit VIa polypeptide 2; targeted mutation 1, Daniel J Garry
MGI ID: MGI:2181189
Synonyms: VIaH-
Gene: Cox6a2  Location: Chr7:128205435-128206387 bp, - strand  Genetic Position: Chr7, 70.04 cM
Germline Transmission:  Earliest citation of germline transmission: J:75606
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA region of exon 2 encoding 97 amino acids was replaced with a PGK-neo cassette. Northern blot analysis of heart and skeletal muscle showed that homozygous mutant mice lacked transcript. (J:75606)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cox6a2 Mutation:  5 strains or lines available
Original:  J:75606 Radford NB, et al., Cardiac dysfunction in mice lacking cytochrome-c oxidase subunit VIaH. Am J Physiol Heart Circ Physiol. 2002 Feb;282(2):H726-33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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