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Clcn5tm1Gug
Targeted Allele Detail
Nomenclature
Symbol: Clcn5tm1Gug
Name: chloride channel 5; targeted mutation 1, William B Guggino
MGI ID: MGI:2181017
Synonyms: ClC-5 KO, Clcn5-, Clcn5 KO
Gene: Clcn5  Location: ChrX:7153810-7319358 bp, - strand  Genetic Position: ChrX, 3.21 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:66560
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (knock-out)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clcn5 Mutation:  13 strains or lines available
References
Original:  J:66560 Wang SS, et al., Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis. Hum Mol Genet. 2000 Dec 12;9(20):2937-45
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory