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Pex11btm1Sjg
Targeted Allele Detail
Nomenclature
Symbol: Pex11btm1Sjg
Name: peroxisomal biogenesis factor 11 beta; targeted mutation 1, Stephen J Gould
MGI ID: MGI:2181008
Synonyms: PEX11beta-
Gene: Pex11b  Location: Chr3:96542692-96552682 bp, + strand  Genetic Position: Chr3, 41.93 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:76782
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1-3 were replaced with a PGK-neo cassette via homologous recombination. Gene expression was absent in liver of homozygous mutant animals as determined by Northern blot analysis. (J:76782)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pex11b Mutation:  10 strains or lines available
References
Original:  J:76782 Li X, et al., PEX11 beta deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function. Mol Cell Biol. 2002 Jun;22(12):4358-65
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory