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Tcratm1Mjo
Targeted Allele Detail
Nomenclature
Symbol: Tcratm1Mjo
Name: T cell receptor alpha chain; targeted mutation 1, Michael J Owen
MGI ID: MGI:2180883
Synonyms: Calpha-, Tcralpha-, TCRalpha, TCRalphae-, TCRalpha KO
Gene: Tcra  Location: unknown  Genetic Position: Chr14, cytoband D1-D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:1292
Parent Cell Line:  GK129 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    The Tcra-C element C1 was disrupted by the insertion of a neomycin selection cassette. (J:1292)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Tcra Mutation:  69 strains or lines available
References
Original:  J:1292 Philpott KL, et al., Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells. Science. 1992 Jun 5;256(5062):1448-52
All:  80 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory