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Targeted Allele Detail
Symbol: Cebpdtm1Aki
Name: CCAAT/enhancer binding protein (C/EBP), delta; targeted mutation 1, Shizuo Akira
MGI ID: MGI:2180837
Synonyms: C/EBPdelta(-)
Gene: Cebpd  Location: Chr16:15887286-15889545 bp, + strand  Genetic Position: Chr16, 10.09 cM
Germline Transmission:  Earliest citation of germline transmission: J:45062
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin selection cassette replaced the region encoding the promoter region, transcription start site, and the transactivation domain. Northern blot analysis of total RNA isolated from the lungs of homozygous mutant mice showed an absence of transcript. (J:45062)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 37 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cebpd Mutation:  4 strains or lines available
Original:  J:45062 Tanaka T, et al., Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. EMBO J. 1997 Dec 15;16(24):7432-43
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory