About   Help   FAQ
Fgf2tm1Bee
Targeted Allele Detail
Summary
Symbol: Fgf2tm1Bee
Name: fibroblast growth factor 2; targeted mutation 1, Friedrich Beerman
MGI ID: MGI:2180834
Synonyms: FGF2-, Fgf2tm1Siec
Gene: Fgf2  Location: Chr3:37402616-37464255 bp, + strand  Genetic Position: Chr3, 18.41 cM, cytoband A2-B
Alliance: Fgf2tm1Bee page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75629
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprt1b-m3
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 of the gene was replaced with a PGK-neo-lacZ cassette via homologous recombination. RT-PCR analysis demonstrated the absence of mRNA in lung and kidney from homozygous mutant animals. (J:75629)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Fgf2tm1Bee
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf2 Mutation:  17 strains or lines available
References
Original:  J:75629 Foletti A, et al., Absence of fibroblast growth factor 2 does not prevent tumor formation originating from the RPE. Oncogene. 2002 Mar 14;21(12):1841-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory