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Targeted Allele Detail
Symbol: Ugcgtm2Rlp
Name: UDP-glucose ceramide glucosyltransferase; targeted mutation 2, Richard L Proia
MGI ID: MGI:2180227
Synonyms: UgcgdeltaEX7Hygro
Gene: Ugcg  Location: Chr4:59189507-59222833 bp, + strand  Genetic Position: Chr4, 32.44 cM, cytoband B3
Germline Transmission:  Earliest citation of germline transmission: J:76736
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsIn mutant embyronic stem cells carrying the targeted mutation Ugcgtm1Rlp, exon 7 of the second allele was targeted using a hygromycin resistance replacement vector. Enzyme assays performed on extracts from doubly mutant embryonic stem cells verified the absence enzyme activity. (J:76736)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ugcg Mutation:  3 strains or lines available
Original:  J:76736 Yamashita T, et al., A vital role for glycosphingolipid synthesis during development and differentiation. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9142-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.15
The Jackson Laboratory