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Targeted Allele Detail
Symbol: Ap1g1tm1Schu
Name: adaptor protein complex AP-1, gamma 1 subunit; targeted mutation 1, Peter Schu
MGI ID: MGI:2180169
Synonyms: gamma-Adaptin -
Gene: Ap1g1  Location: Chr8:109778554-109864204 bp, + strand  Genetic Position: Chr8, 57.26 cM
Germline Transmission:  Earliest citation of germline transmission: J:53252
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe insertion of a neomycin selection cassette disrupted the exon that encodes amino acid residues 68 through 108. Northern and Western analyses of heterozygous animals showed roughly 70% and 50% reductions in expression, respectively. (J:53252)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ap1g1 Mutation:  28 strains or lines available
Original:  J:53252 Zizioli D, et al., Early embryonic death of mice deficient in gamma-adaptin. J Biol Chem. 1999 Feb 26;274(9):5385-90
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.06
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