About   Help   FAQ
Aldh5a1tm1Kmg
Targeted Allele Detail
Nomenclature
Symbol: Aldh5a1tm1Kmg
Name: aldhehyde dehydrogenase family 5, subfamily A1; targeted mutation 1, K Michael Gibson
MGI ID: MGI:2180159
Synonyms: Aldh5a1-, SSADH-, SSADH-deficient
Gene: Aldh5a1  Location: Chr13:24907579-24937661 bp, - strand  Genetic Position: Chr13, 10.77 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71949
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aldh5a1 Mutation:  3 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Epilepsy (J:91856)

References
Original:  J:71949 Hogema BM, et al., Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase. Nat Genet. 2001 Oct;29(2):212-6
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory