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Adam9tm1Bbl
Targeted Allele Detail
Nomenclature
Symbol: Adam9tm1Bbl
Name: a disintegrin and metallopeptidase domain 9 (meltrin gamma); targeted mutation 1, Carl Blobel
MGI ID: MGI:2180096
Synonyms: mdc9-
Gene: Adam9  Location: Chr8:24949611-25016882 bp, - strand  Genetic Position: Chr8, 13.7 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:74655
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin resistance gene was inserted into the exon encoding amino acids 32 through 66. Protein expression was undetectable in lung and brain tissue isolated from homozygous mutants and in tissue from homozygous mutant embryos. (J:74655)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adam9 Mutation:  21 strains or lines available
References
Original:  J:74655 Weskamp G, et al., Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life. Mol Cell Biol. 2002 Mar;22(5):1537-44
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory