Tg(Cga-cre)3Sac
Transgene Detail

Summary

• Symbol: Tg(Cga-cre)3Sac
• Name: transgene insertion 3, Sally A Camper
• MGI ID: MGI:2179995
• Synonyms: alphaGSU-cre, S3, TgN(Cga-cre)^S3Sac
• Transgene: Tg(Cga-cre)3Sac Location: unknown
• Alliance: Tg(Cga-cre)3Sac page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Cga-cre)3Sac expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cga (MGI:88390)

• Mutation details: This transgene expresses Cre recombinase under the control of a mouse glycoprotein hormone alpha-subunit (Cga) gene. This promoter is active in the pituitary primordium beginning at embryonic day 9.5. Cre recombinase expression is detected in the anterior and intermediate lobes of the pituitary gland, in cardiac, and in skeletal muscle. Low to no level of expression is detected in the posterior pituitary, lungs, kidneys, brain, adrenal glands, and gonads. (J:66897)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cga (mouse) Summary of all recombinase alleles driven by Cga. Comparative matrix view of recombinase activities Alliance mouse Cga gene page

Disease models

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Hemizygous transgenic mice are viable, fertile, normal in size, and do not display any gross physical or behavioral abnormalities.

References

• Original: J:66897 Cushman LJ, et al., Cre-mediated recombination in the pituitary gland. Genesis. 2000 Nov-Dec;28(3-4):167-74
• All: 17 reference(s)