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Targeted Allele Detail
Symbol: Ptger2tm1Brey
Name: prostaglandin E receptor 2 (subtype EP2); targeted mutation 1, Richard M Breyer
MGI ID: MGI:2179967
Synonyms: EP2-
Gene: Ptger2  Location: Chr14:44988195-45003820 bp, + strand  Genetic Position: Chr14, 22.68 cM
Germline Transmission:  Earliest citation of germline transmission: J:53646
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA PGK-neomycin resistance cassette replaced part of the amino terminal coding sequence, including 420 bp from the ATG start codon to codon 140. (J:53646)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptger2 Mutation:  5 strains or lines available
Original:  J:53646 Kennedy CR, et al., Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor. Nat Med. 1999 Feb;5(2):217-20
All:  35 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory