About   Help   FAQ
S100a8tm1Hume
Targeted Allele Detail
Summary
Symbol: S100a8tm1Hume
Name: S100 calcium binding protein A8 (calgranulin A); targeted mutation 1, David A Hume
MGI ID: MGI:2179780
Gene: S100a8  Location: Chr3:90576378-90577341 bp, + strand  Genetic Position: Chr3, 39.9 cM, cytoband F1-F2
Alliance: S100a8tm1Hume page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:56750
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exon 2, which contains the majority of the coding sequence of the gene. (J:56750)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any S100a8 Mutation:  7 strains or lines available
References
Original:  J:56750 Passey RJ, et al., A null mutation in the inflammation-associated S100 protein S100A8 causes early resorption of the mouse embryo. J Immunol. 1999 Aug 15;163(4):2209-16
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory