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Targeted Allele Detail
Symbol: Syngr1tm1Sud
Name: synaptogyrin 1; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:2179744
Gene: Syngr1  Location: Chr15:79975535-80003702 bp, + strand  Genetic Position: Chr15, 37.85 cM
Germline Transmission:  Earliest citation of germline transmission: J:58559
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance cassette replaced exon II and flanking sequences, which encodes two transmembrane domains of the encoded protein. Western blot analysis on total brain protein confirmed that no detectable encoded protein was present in homozygous mice. (J:58559)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Syngr1 Mutation:  34 strains or lines available
Original:  J:58559 Janz R, et al., Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron. 1999 Nov;24(3):687-700
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory