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Syngr1tm1Sud
Targeted Allele Detail
Nomenclature
Symbol: Syngr1tm1Sud
Name: synaptogyrin 1; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:2179744
Gene: Syngr1  Location: Chr15:80091334-80119501 bp, + strand  Genetic Position: Chr15, 37.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58559
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exon II and flanking sequences, which encodes two transmembrane domains of the encoded protein. Western blot analysis on total brain protein confirmed that no detectable encoded protein was present in homozygous mice. (J:58559)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Syngr1 Mutation:  27 strains or lines available
References
Original:  J:58559 Janz R, et al., Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron. 1999 Nov;24(3):687-700
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory