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Erbb2tm2Mul
Targeted Allele Detail
Nomenclature
Symbol: Erbb2tm2Mul
Name: erb-b2 receptor tyrosine kinase 2; targeted mutation 2, William Muller
MGI ID: MGI:2179519
Synonyms: erbB-2KI/KI
Gene: Erbb2  Location: Chr11:98412470-98437716 bp, + strand  Genetic Position: Chr11, 61.75 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:74283
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Exon 1 was targeted with a PGK-neo cassette preceded by a wild-type cDNA copy of the gene. (J:74283)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Erbb2 Mutation:  32 strains or lines available
References
Original:  J:74283 Chan R, et al., The Catalytic Activity of the ErbB-2 Receptor Tyrosine Kinase Is Essential for Embryonic Development. Mol Cell Biol. 2002 Feb;22(4):1073-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory