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Foxf1tm1Rhc
Targeted Allele Detail
Nomenclature
Symbol: Foxf1tm1Rhc
Name: forkhead box F1; targeted mutation 1, Robert H Costa
MGI ID: MGI:2179135
Synonyms: Foxf1-
Gene: Foxf1  Location: Chr8:121084386-121088144 bp, + strand  Genetic Position: Chr8, 70.31 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:70364
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe genomic sequences encoding the N-terminal winged-helix DNA binding domain are replaced with a cassette containing a LacZ gene with a nuclear localization sequence and a PGK/neo gene. (J:70364)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 68 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxf1 Mutation:  1 strain or line available
References
Original:  J:70364 Kalinichenko VV, et al., Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the Forkhead Box f1 transcription factor. Dev Biol. 2001 Jul 15;235(2):489-506
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory