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Ripk1tm1Led
Targeted Allele Detail
Nomenclature
Symbol: Ripk1tm1Led
Name: receptor (TNFRSF)-interacting serine-threonine kinase 1; targeted mutation 1, Philip Leder
MGI ID: MGI:2179109
Synonyms: rip -, RIP1-
Gene: Ripk1  Location: Chr13:34002363-34035170 bp, + strand  Genetic Position: Chr13, 14.01 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46522
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance gene was inserted into exon 2, 50 bp after the initiation codon. (J:46522)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ripk1 Mutation:  15 strains or lines available
References
Original:  J:46522 Kelliher MA, et al., The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity. 1998 Mar;8(3):297-303
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory