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Targeted Allele Detail
Symbol: Cer1tm1Bhr
Name: cerberus 1, DAN family BMP antagonist; targeted mutation 1, Richard R Behringer
MGI ID: MGI:2178818
Synonyms: Cerl-, Cerr1-
Gene: Cer1  Location: Chr4:82881751-82885148 bp, - strand  Genetic Position: Chr4, 39.4 cM
Germline Transmission:  Earliest citation of germline transmission: J:62080
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA PGKneobpA-lox cassette replaced the entire gene coding region via homologous recombination. Southern blot analysis using a 5' cDNA fragment as a probe confirmed the deletion of the coding region in homozygous mutant embryos. (J:62080)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cer1 Mutation:  7 strains or lines available
Original:  J:62080 Shawlot W, et al., The cerberus-related gene, Cerr1, is not essential for mouse head formation [letter]. Genesis. 2000 Apr;26(4):253-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory