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Tlr2tm1Aki
Targeted Allele Detail
Nomenclature
Symbol: Tlr2tm1Aki
Name: toll-like receptor 2; targeted mutation 1, Shizuo Akira
MGI ID: MGI:2178675
Synonyms: Tlr2-, TLR2KO, TLR2 KO
Gene: Tlr2  Location: Chr3:83836272-83841608 bp, - strand  Genetic Position: Chr3, 37.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:76115
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Tlr2 Mutation:  11 strains or lines available
References
Original:  J:76115 Takeuchi O, et al., Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity. 1999 Oct;11(4):443-51
All:  479 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory