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Targeted Allele Detail
Symbol: Clec3btm1Umw
Name: C-type lectin domain family 3, member b; targeted mutation 1, Ulla M Wewer
MGI ID: MGI:2178555
Synonyms: Tet -, Tnatm1Umw
Gene: Clec3b  Location: Chr9:123150946-123157430 bp, + strand  Genetic Position: Chr9, 73.91 cM, cytoband F1-F3
Germline Transmission:  Earliest citation of germline transmission: J:72638
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe transcription start site and exon 1 (which contains the translation start site) were replaced by a neo cassette. RT-PCR and Northern blot analyses demonstrated absence of transcript from several tissues in homozygous mutant mice. Western blotting verified absence of protein from serum in mutant mice. (J:72638)
View phenotypes for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clec3b Mutation:  3 strains or lines available
Original:  J:72638 Iba K, et al., Mice with a targeted deletion of the tetranectin gene exhibit a spinal deformity. Mol Cell Biol. 2001 Nov;21(22):7817-25
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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