Mycltm1Rdp
Targeted Allele Detail
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Symbol: |
Mycltm1Rdp |
Name: |
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived; targeted mutation 1, Ronald DePinho |
MGI ID: |
MGI:2178221 |
Synonyms: |
L-myc - |
Gene: |
Mycl Location: Chr4:122889445-122896278 bp, + strand Genetic Position: Chr4, 57.36 cM
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Alliance: |
Mycltm1Rdp page
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Germline Transmission: |
Earliest citation of germline transmission:
J:31946
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A 19 bp oligonucleotide containing a restriction site and a translation termination codon was inserted into exon 2. In addition, part of exon 3 was replaced with a neomycin resistance cassette. Northern blot and western blot analysis confirmed that no detectable transcript or protein was expressed from this allele.
(J:31946)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mycl Mutation: |
19 strains or lines available
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Original: |
J:31946 Hatton KS, et al., Expression and activity of L-Myc in normal mouse development. Mol Cell Biol. 1996 Apr;16(4):1794-804 |
All: |
1 reference(s) |
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