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Tg(Pgk1-cre)1Lni
Transgene Detail
Nomenclature
Symbol: Tg(Pgk1-cre)1Lni
Name: transgene insertion 1, Peter Lonai
MGI ID: MGI:2178050
Synonyms: Cremat, PGKCre, PGK-Cre, PGK:Cre, PGK-Crem
Transgene: Tg(Pgk1-cre)1Lni  Location: unknown  Genetic Position: Chr4, Syntenic
Transgene
origin
Strain of Origin:  (BALB/c x C57BL/6)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThis transgene directs the expression of Cre recombinase under the control of a phosphoglycerate kinase promoter, with integration site effects. Expression of this transgene is under dominant maternal control, probably due to cis acting effects at the integration site. SNP typing indicates that it is likely the transgene integrated into a Chr 4 locus of BALB/c origin. Activity is thought to commence at the diploid phase of oogenesis, and directs complete recombination in all tissues of progeny derived from mothers carrying the transgene. (J:69332)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pgk1     Summary of all recombinase alleles driven by Pgk1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:69332 Lallemand Y, et al., Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase. Transgenic Res. 1998 Mar;7(2):105-12
All:  172 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory