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F3tm1.1Dwr
Targeted Allele Detail
Nomenclature
Symbol: F3tm1.1Dwr
Name: coagulation factor III; targeted mutation 1.1, Mieke Dewerchin
MGI ID: MGI:2178048
Synonyms: TFdeltaCT
Gene: F3  Location: Chr3:121723537-121735048 bp, + strand  Genetic Position: Chr3, 52.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71271
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis allele is a derivative of F3tm1Dwr in which the loxP-flanked neomycin resistance cassette was deleted in the germline by Cre mediated recombination. (J:71271)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any F3 Mutation:  11 strains or lines available
References
Original:  J:71271 Melis E, et al., Targeted deletion of the cytosolic domain of tissue factor in mice does not affect development. Biochem Biophys Res Commun. 2001 Aug 24;286(3):580-6
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory