About   Help   FAQ
Etv6tm1Sho
Targeted Allele Detail
Nomenclature
Symbol: Etv6tm1Sho
Name: ets variant 6; targeted mutation 1, Stuart H Orkin
MGI ID: MGI:2177950
Synonyms: TEL -
Gene: Etv6  Location: Chr6:134035700-134270158 bp, + strand  Genetic Position: Chr6, 64.58 cM, cytoband G2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:42409
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced a DNA segment that contains exons coding for the DNA-binding domain. Northern blot and RT-PCR analysis on RNA derived from double-targeted ES cells demonstrated that no detectable transcript was produced from this allele. (J:42409)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Etv6 Mutation:  134 strains or lines available
References
Original:  J:42409 Wang LC, et al., Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL. EMBO J. 1997 Jul 16;16(14):4374-83
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/13/2017
MGI 6.11
The Jackson Laboratory