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Pin1tm1Tuc
Targeted Allele Detail
Nomenclature
Symbol: Pin1tm1Tuc
Name: protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; targeted mutation 1, Takafumi Uchida
MGI ID: MGI:2177943
Synonyms: Pin1-
Gene: Pin1  Location: Chr9:20652130-20666584 bp, + strand  Genetic Position: Chr9, 7.6 cM
Reduced body weight and testicular atrophy in Pin1tm1Tuc/Pin1tm1Tuc mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58734
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pin1 Mutation:  18 strains or lines available
References
Original:  J:58734 Fujimori F, et al., Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest. Biochem Biophys Res Commun. 1999 Nov 30;265(3):658-63
All:  39 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory