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Lmnatm1Stw
Targeted Allele Detail
Nomenclature
Symbol: Lmnatm1Stw
Name: lamin A; targeted mutation 1, Colin L Stewart
MGI ID: MGI:2177930
Synonyms: Lmna-
Gene: Lmna  Location: Chr3:88481148-88509956 bp, - strand  Genetic Position: Chr3, 38.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58702
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lmna Mutation:  58 strains or lines available
References
Original:  J:58702 Sullivan T, et al., Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J Cell Biol. 1999 Nov 29;147(5):913-20
All:  33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory